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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TQ0265 | Indolelactic acid | Endogenous Metabolite | |
Indolelactic acid is a metabolite of tryptophan in Azotobacter vinelandii cultures. | |||
T17099 | Timapiprant sodium | OC000459 sodium | Others |
Timapiprant sodium inhibits mast cell activation of Th2 lymphocytes and eosinophils. Timapiprant sodium is a potent and selective D prostanoid receptor 2 antagonist. Timapiprant sodium potently displaces [3H] PGD2 from h... | |||
T11482 | GSK2245035 | Others | |
GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα). It effectively suppresses allergen-induced Th2 cytokine p... | |||
T10890 | CRTh2 antagonist 3 | Others | |
CRTh2 antagonist 3 is a powerful chemokine receptor homologous molecule expressed on Th2 cell (CRTh2) antagonists. CRTh2 antagonist 3 enhanced the activity of PDK1 on short peptide substrates with EC50 of 2 μM and Kd of ... | |||
T38838 | QS-21 | Stimulon,QS-21 | |
QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, Q... | |||
T82882 | Binetrakin | ||
Binetrakin (Interleukin 4 (human)) is a pleiotropic cytokine derived from T lymphocytes that influences multiple cell types, such as B cells and T cells, and promotes the differentiation of naive helper T cells (Th0 cell... | |||
T62860 | YM-341619 | ||
YM-341619 (AS1617612) is a potent, orally active STAT6 inhibitor (IC50: 0.70 nM). YM-341619 inhibits IL-4-induced Th2 differentiation in mouse splenic T cells with an IC50 value of 0.28 nM, but does not affect Th1 cell d... | |||
T81314 | Rademikibart | CBP-201 | |
Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, without cross-reactivity to IL-4Rα from other species. It effectively... | |||
TN4778 | Physalin H | gp120/CD4 , Antifection , Autophagy | |
Physalin H is an Hh signaling inhibitor blocks GLI1-DNA-complex formation, it also strong quinone reductase induction activity with IR (Induction ratio, QR induction activity) value of 3.74±0.02. Physalin H shows immunos... |